Low AMH and failed IVF

in In vitro fertilisation edited November 2016
Hi, I have AMH 1.9 . Despite recently having IVF and 2 good embryos it failed. How do we know if it was the egg quality or failure to implant that caused the failure? Are there any tests that can be done to look at implantation success. My consultant thinks I have autoimmune disease that has affected my ovaries- are there tests for this and what could the possible implications for getting and staying pregnant?
Thanks you in advance of your reply.
  • edited January 2014
    Dear Gilly,

    Thanks for your question, we appreciate your sharing your case with us.

    I do not have all the information to give you an accurate answer for your specific case, for example your age, which is a very important factor regarding the results of an IVF treatment.

    However, your AMH levels are low and this could be related to a bad egg quality. The main cause for a failed IVF is usually the poor quality of the eggs and therefore the embryos, but it is true that some autoimmune alterations or coagulation factor mutations could also affect the capacity to implant of your uterus and increase the risk of miscarriage in case of pregnancy. 

    To rule out this uterine factor, after several IVF failures we usually advise to do a hysteroscopy with an endometrial biopsy to check the uterine cavity and the quality of the endometrium and also a blood test including the karyotype, the thyroid function and the detection of antibodies and coagulation factors that could be altered (Protein C, Protein S, Prothrombine’s gen mutation, Antithrombin III, ANA, etc...). 

    I hope to have been of assistance to you, if you have any other queries or questions, please feel free to share them with us.

    Best regards,

    Dr. Clara Colomé
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